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Do potassium-sparing diuretics interact with any other medications?

Donna Hill Howes, RN
Family Practitioner

If you are taking cyclosporine, a potassium replacement, or tacrolimus, amiloride can lead to side effects and should be avoided.

If you are taking an opioid, amiloride and triamterene may not be good options for you.

If you are taking spironolactone, you should not take amiloride or triamterene. 

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor. 

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.