What is the treatment for invasive lobular carcinoma (ILC)?

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Penn Medicine
Administration
There are a number of possible treatments for invasive (infiltrating) lobular carcinoma (ILC). Treatments for stages I, II and III and operable stage III may include:
  • Breast-conserving surgery to remove only the cancer and some surrounding breast tissue, followed by lymph node dissection and radiation therapy
  • Modified radical mastectomy with or without breast reconstruction surgery
  • Sentinel lymph node biopsy followed by surgery
  • Adjuvant therapy (treatment given after surgery to increase the chances of a cure) that may include: radiation therapy to the lymph nodes near the breast and to the chest wall after a modified radical mastectomy, systemic chemotherapy with or without hormone therapy, hormone therapy
  • Clinical trials
Treatment of stage IIIB and inoperable stage IIIC breast cancer may include:
  • Systemic chemotherapy
  • Systemic chemotherapy followed by surgery (breast-conserving surgery or total mastectomy), with lymph node dissection followed by radiation therapy
  • Additional systemic therapy (chemotherapy, hormone therapy or both)
  • Clinical trials
Treatment of stage IV or metastatic breast cancer may include the following:
  • Hormone therapy and/or systemic chemotherapy
  • Radiation therapy and/or surgery for relief of pain and other symptoms
  • Clinical trials

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.