What to know about smoking and risk for breast cancer

Studies tie tobacco use to an increased risk of breast cancer. Find out why, and get help quitting tobacco with these tips.

Updated on October 29, 2025.

Many leading health organizations routinely publish lists of breast cancer risk factors, which are traits or habits that increase your risk of developing the disease. Since it’s so strongly associated with other cancers, it may come as a surprise that smoking doesn't appear on these lists.

  • The American Cancer Society (ACS) doesn’t list tobacco use among lifestyle risk factors, instead placing it on a list of factors with “unclear” effects on breast cancer risk.
  • The Centers for Disease Control and Prevention (CDC) mentions that smoking “may” increase this risk. It’s listed behind other lifestyle habits with a more certain effect, such as being physically inactive and drinking alcohol.
  • The National Cancer Institute says that cigarette smoking and exposure to secondhand smoke “have little or no effect on the risk of breast cancer.”

That said, some prominent groups do recognize a connection. The World Health Organization (WHO), for example, states unequivocally that “certain factors increase the risk of breast cancer” and lists tobacco use among these.

Evidence for a connection between smoking and breast cancer

Despite the lack of consensus, evidence continues to build supporting a connection between smoking and increased risk for breast cancer. For example:

  • A review of 214 studies published in 2020 in the Asian Pacific Journal of Cancer Prevention found that exposure to tobacco smoke was linked to a higher risk of breast cancer in women in Asia.
  • Another study published in the British Journal of Cancer in 2021 looked at over 100,000 cases of invasive breast cancer (cancer that starts in one part and spreads to other parts of the breast) and found evidence to support long-term smoking as a risk factor, even for those who had quit.
  • One study published in 2023 in the journal Tobacco Induced Diseases suggested that menopause plays into risk. Researchers found that premenopausal women who smoked had a higher breast cancer risk than those who didn’t smoke. For postmenopausal women who were overweight or obese, however, the risk was lower than women who didn’t smoke. Despite this potential small protective effect seen in postmenopausal women, researchers cautioned that smoking's effects on the rest of the body outweigh any benefit.

Smoking may also make an already-established cancer even worse. A 2021 study published in Nature Communications found a clear link between nicotine—the main addictive ingredient in cigarettes—and breast cancer tumors spreading to the lungs.

How to quit tobacco

Smoking is considered to be a major risk factor for many diseases aside from breast cancer, including heart disease, stroke, chronic obstructive pulmonary disease (COPD, a chronic disease that permanently damages the lungs), and lung cancer. By quitting tobacco, you can lower your odds of developing these conditions—often significantly.

While different quit strategies work for different people, the following tips may be effective.

Find your reason for quitting

Telling yourself you “shouldn’t” smoke may not provide the motivation you need. Your reasoning reflects what’s most important to you—and can include:

  • Living a healthier lifestyle
  • Having more energy
  • Saving money
  • Setting a good example or being there for your family

Create a plan

Preparing a quit plan will help you anticipate issues and come up with solutions. To build a successful quit plan:

  • Pick a specific quit date.
  • Tell loved ones—and let them know how they can help. Try making a support list including friends, family, phone numbers, and support groups.
  • Get rid of reminders including ashtrays, lighters, and even the smell of smoke in your car, clothes, and furniture.
  • Figure out what your triggers are. Which activities, situations, or people are often linked to cravings for a cigarette? Think about ways to deal with these factors.
  • Assemble a toolkit to help with withdrawal. It may include quit-smoking medications, distractions when you feel a craving, and safe substitutes for cigarettes like gum or drinking water.
  • Plan rewards for when you meet goals.

While more research is needed to fully understand the link between smoking and breast cancer, quitting will lower your risk of getting many other types of cancers and health conditions. And you may even reverse your risk—20 years after quitting, your risk for many cancers drops to nearly the same as someone who has never smoked.

Article sources open article sources

American Cancer Society. Lifestyle-related Breast Cancer Risk Factors. May 5, 2025.
American Cancer Society. Factors with Unclear Effects on Breast Cancer Risk. May 5, 2025.
Centers for Disease Control and Prevention. Breast Cancer Risk Factors? September 22, 2025.
National Cancer Institute. Breast Cancer Prevention (PDQ)–Patient Version. May 8, 2025.
World Health Organization. Breast Cancer. August 14, 2025.
Gram IT, Park SY, Maskarinec G, et al. Smoking and breast cancer risk by race/ethnicity and oestrogen and progesterone receptor status: the Multiethnic Cohort (MEC) study. Int J Epidemiol. 2019 Apr 1;48(2):501-511.
Youn HJ, Han W. A Review of the Epidemiology of Breast Cancer in Asia: Focus on Risk Factors. Asian Pac J Cancer Prev. 2020;21(4):867-880.
Park HA, Neumeyer S, Michailidou K, et al. Mendelian randomization study of smoking exposure in relation to breast cancer risk. Br J Cancer. 2021;125(8):1135-1145.
Peñalver-Argüeso B, García-Esquinas E, et al. Smoking history and breast cancer risk by pathological subtype: MCC-Spain study. Tob Induc Dis. 2023 Nov 30;21:157.
Tyagi A, Sharma S, Wu K, et al. Nicotine promotes breast cancer metastasis by stimulating N2 neutrophils and generating pre-metastatic niche in lung. Nat Commun. 2021;12(1):474.
Centers for Disease Control and Prevention. Smoking and Cancer. February 24, 2025.
Centers for Disease Control and Prevention. How to Quite Smoking. May 15, 2024.
Centers for Disease Control and Prevention. Tips for Quitting. September 27, 2024.
Centers for Disease Control and Prevention. Benefits of quitting. May 15, 2024.

 

More On

A potential risk factor for breast cancer has been identified, study suggests

video

A potential risk factor for breast cancer has been identified, study suggests
Researchers believe they have identified a risk factor for breast cancer - loss of breast density.
Continuing to work when you have metastatic breast cancer

article

Continuing to work when you have metastatic breast cancer
Seven things people with metastatic breast cancer should consider when making decisions about work.
6 ways to help a loved one with breast cancer

slideshow

6 ways to help a loved one with breast cancer
Give your friend or family member the support they really need through a difficult time.
Questions to ask your medical team

video

Questions to ask your medical team
Kristi Funk, MD equips viewers with essential questions to ask their medical team when facing a breast cancer diagnosis.
Katie Couric and her breast cancer journey

video

Katie Couric and her breast cancer journey
Couric says that she went in for a routine mammogram in June. She describes the discovery, shock and treatment in order to educate other women.