Who is a candidate for yttrium-90 therapy for liver disease?

Yttrium-90 can be used in people who have intermediate liver disease and do not qualify for transplantation.  In these people yttrium-90 can be used to downstage their disease. Yttrium-90 can be used for palliation to improve overall survival, but not with a curative intent or to palliate tumor related symptoms.

Yttrium-90 is primarily used in people with chemo-refractory tumors in the liver, or who have failed second or third line chemotherapies. This is called salvage therapy, and it does improve survival in that setting. It can also be used in people who are intolerant to chemotherapy, which either could be first line, second line, or third line. It can be used as a chemo-vacation as a maintenance therapy between chemotherapy doses, and can be used for consolidation therapy.

Trinity Health is a Catholic health care organization that acts in accordance with the Catholic tradition and does not condone or support all practices covered in this site. In case of emergency call 911. This site is educational and not a substitute for professional medical advice, always seek the advice of a qualified health care provider.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.