Who handles stress better, men or women?

Research is showing us that men handle stress better than women. Dr. Rita Valentino led a rat study, published in Molecular Psychiatry. She discovered when both sexes were stressed, females experienced twice the stress compared to males. Females were more sensitive to the stress-related hormone known as corticotrophin-releasing factor (CRF).  Dr. Valentino believes these findings could be relevant for humans.  CRF plays a role in our experience of stress and lack of effective CRF regulation is often characteristic of stress-related mental disorders.