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What is the role of neurotransmitters in premature ejaculation?

Madeleine M. Castellanos, MD
Psychiatry
The neurotransmitters (chemical messengers) serotonin and dopamine appear to be involved in premature ejaculation (PE). Serotonin increases ejaculatory threshold and delays ejaculation and orgasm while dopamine decreases them. The proper balance of both neurotransmitters is necessary for optimal sexual function. Men with PE have been shown to have lower levels of serotonin, which may help explain why they ejaculate too quickly.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.