Which blood pressure medicine is most likely to cause ED?

Diuretics (water pills) and b-adrenergic (beta) blockers are most likely to cause erectile dysfunction (ED). Diuretics, like spironolactone (Aldactone) and thiazides (Diuril and Naturetin), decrease blood flow to the penis, which makes it difficult to get or maintain an erection. Diuretics also lower levels of zinc in the body, a mineral that is needed to make the male hormone testosterone. Beta blockers, like propranolol (Inderal) and metoprolol (Lopressor), can lower response to nerve impulses that lead to an erection and keep the blood vessels in the penis from becoming wide enough to allow enough blood flow for an erection.
Dr. Mehmet Oz, MD
Cardiology (Cardiovascular Disease)
Two common treatments for high blood pressure can contribute to erectile dysfunction (ED). They are thiazide diuretics and beta blockers. Both have been around for a long time and are effective at controlling blood pressure. But they aren't the only blood pressure medications available.

If you are experiencing ED, talk to your doctor to see if there is another high blood pressure medication you should try. Remember that high blood pressure itself can contribute to ED, so treating your blood pressure with the right medication is an important part of treating your ED. Don't just stop taking your meds, especially something as important as high blood pressure medication. Stopping your blood pressure medications 'cold turkey' is dangerous and can actually make your blood pressure sky rocket, putting you at risk for a heart attack or a stroke. So do talk to your doctor about alternatives.

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