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Which blood pressure medicine is most likely to cause ED?

Diuretics (water pills) and b-adrenergic (beta) blockers are most likely to cause erectile dysfunction (ED). Diuretics, like spironolactone (Aldactone) and thiazides (Diuril and Naturetin), decrease blood flow to the penis, which makes it difficult to get or maintain an erection. Diuretics also lower levels of zinc in the body, a mineral that is needed to make the male hormone testosterone. Beta blockers, like propranolol (Inderal) and metoprolol (Lopressor), can lower response to nerve impulses that lead to an erection and keep the blood vessels in the penis from becoming wide enough to allow enough blood flow for an erection.

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