Which medications frequently result in erectile dysfunction?

Both over-the-counter (OTC) and prescription medications can cause erectile dysfunction (ED). OTC products that can cause problems getting and keeping an erection include ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs), and  antihistamines (such as Benadryl, Dramamine, Tagamet, and Zyrtec). Among the prescription drugs that cause ED are antidepressants, chemotherapy agents and opiate analgesics (including codeine, morphine and oxycodone). Several medications to treat high blood pressure also cause ED. Among them: diuretics, like spironolactone (Aldactone) and thiazides (Diuril and Naturetin); centrally-acting agents, like methyldopa (Aldomet) and reserpine (Serpasil and Raudixin); a-adrenergic (alpha) blockers, like prazosin (Minipress) and terazosin (Hytrin); and b-adrenergic (beta) blockers, like propranolol (Inderal) and metoprolol (Lopressor).