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Can B vitamins make pain relievers more effective?

B vitamins may enhance the effects of certain pain relievers. Some research indicates that in people who suffer low back pain, taking a supplement containing vitamins B1, B6 and B12 along with a nonsteroidal anti-inflammatory drug (NSAID) provided better pain relief than the NSAID alone and reduced the need for the NSAID among study participants. Ibuprofen is one example of an NSAID.

B vitamins may also have direct effects on the nervous system. There is some evidence that taking B vitamins may reduce the pain of neuropathy (nerve pain) in people with diabetes or in people who are deficient in these vitamins. Talk to your doctor about whether taking B vitamin supplements is right for you.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.