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Vitamin B12 supplements may reduce the absorption and effectiveness of some antibiotics, and the antibiotics can interfere with absorption of vitamin B12 (and other B vitamins) from supplements, so the two pills should not be taken at the same time.
Other medications can also interfere with your uptake of vitamin B12, possibly raising your risk for deficiency. These medications include antacids and peptic ulcer medications, cholesterol-lowering drugs, antiseizure medications, chemotherapy medications, the diabetes treatment glucophage (Metformin) and others.
Drinking excessive amounts of alcohol may also interfere with absorption of the vitamin from food, increasing your risk for B12 deficiency. Make sure your doctor is aware of any medications or supplements that you take.
This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.