What Do Neurodegenerative Diseases Have in Common?
Parkinson's disease, Alzheimer's disease and dementia all appear to have something in common. In this video, Walter J. Koroshetz, MD, director of the NINDS, reveals what that is and how it leads to nerve cell death, or neurodegeneration.
Transcript
So the interesting thing is that all the neurodegenerative diseases, they're all characterized by one thing,
and that's the aggregation of a protein inside the nerve cells. And those nerve cells then die when that happens.
So in Parkinson's, it's nuclein. In Alzheimer's, it's tau inside the neurons. And if you look at people who die with dementia,
a number of them have both. And so I think that they're not completely independent problems.
But they're both related to the cell, the neurons inability to clear these aggregated proteins, which
brain health nervous system
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