Who should not take vitamin B9?

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Stacy Wiegman, PharmD
Pharmacy Specialist

Generally speaking, vitamin B9 (folic acid) is very safe, but you should talk to your doctor before using it if you have pernicious anemia, hemolytic anemia, alcoholism, infections or kidney problems. Some medications may also negatively interact with folic acid, including phenytoin, primidone, methotrexate, barbiturates, nitrofurantoin, tetracycline and pyrimethamine. If you are taking any of these medications, talk to your doctor before using folic acid.

Everyone needs vitamin B9 but for many anemias, vitamin B9 is best used in conjunction with vitamin B12. Additionally, people with pernicious anemia (who have B12 antibodies) should not take vitamin B9 alone as it can potentially worsen pernicious anemia and cause nerve damage.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.