What are some natural dermal fillers?

Patricia Farris, MD

There are two natural dermal fillers, collagen and hyaluronic acid. Collagen based fillers were among the first in the marketplace and are used by dermatologists to fill superficial facial lines and wrinkles. The collagen fillers used today are human collagen so there is no need for skin testing and little chance for allergic reactions. Hyaluronic acid (HA) is a naturally occurring polysaccharide that is cross linked and stablized to form a filler. HA fillers are the most widely used dermal fillers because they are safe, versatile and last longer than collagen fillers. HA fillers can be used to fill lines and wrinkles, add volume to the face and to enhance the lips. 

There are many natural dermal fillers a patient may choose from. Learn more from Dr. Jeremy Warner from NorthShore University HealthSystem about natural dermal fillers.
Daniel Kapp
Daniel Kapp on behalf of MDLIVE
Plastic & Reconstructive Surgery

Hyaluronic acid is the most common natural filler.  Hyaluronic acid is also known as extracellular matrix.  It is a gel-like material which is found normally in the body and is the consistency of a thick gel.  In the past hyaluronic acids have been of animal origin.  However, today most hyaluronic acids on the market are genetically engineered.  The infection risk and the cross-reactivity is almost zero.


Dr. Mehmet Oz, MD
Cardiology (Cardiovascular Disease)
Collagen is a protein found naturally in our bodies. It keeps our skin strong, firm and flexible. We lose collagen as we age, so some people receive collagen injections to replace what they have lost. Another natural filler is hyaluronic acid. It not only works to fill in wrinkles, but some research suggests it can also help promote new collagen growth.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.