What medications can be used to treat frontotemporal dementia (FTD)?

David A. Merrill, MD
Cognitive enhancers were not developed to treat frontotemporal dementia (FTD). As such, there's limited to no evidence supporting their use. However, if a person has two conditions occurring at once, such as FTD and Alzheimer's disease or a frontal variant of Alzheimer's, they may want to try cognitive enhancers. An evaluation is critical to determine whether or not to try these medications in these cases.

There's some support for the use of antidepressants and weaker evidence for antipsychotics. It's not known whether mood stabilizers are helpful. As the symptoms of FTD get more severe, families and doctors tend to be compelled to try different medications. It is reasonable to try them if the risk-benefit isn't in favor of preserving independence.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.