Dx Dialogues: autoantibody tests and the importance of early-stage detection of T1D

Sanda Sobel, MD, explains how autoantibody tests can help assess a patient's risk for type 1 diabetes, before they present in diabetic ketoacidosis.

Transcript

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Traditionally in the diagnosis of type 1 diabetes, we had to wait until an individual presented in diabetic ketoacidosis.

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[MUSIC PLAYING] We now can screen for type 1 diabetes using blood tests that

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are checking for antibodies, zinc transporter 8, GAD65, insulin autoimmune antibody, as well

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as the islet cell antigen. We can now capture individuals who are at risk prior to the progression

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of diabetic ketoacidosis. Ultimately, the goal is in earlier detection of type

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1 diabetes in stage 1 or stage 2, we can preserve beta cell mass for longer. [AUDIO LOGO]