LEVOFLOXACIN (lee voe FLOX a sin) treats infections caused by bacteria. It belongs to a group of medications called quinolone antibiotics. It will not treat colds, the flu, or infections caused by viruses.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

They need to know if you have any of these conditions: • Bone problems • Diabetes • Heart disease • High blood pressure • History of irregular heartbeat • History of low levels of potassium in the blood • Joint problems • Kidney disease • Liver disease • Mental illness • Myasthenia gravis • Seizures • Tendon problems • Tingling of the fingers or toes, or other nerve disorder • An unusual or allergic reaction to levofloxacin, other quinolone antibiotics, foods, dyes, or preservatives • Pregnant or trying to get pregnant • Breast-feeding

Take this medication by mouth with a full glass of water. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Take your medication at regular intervals. Do not take your medication more often than directed. Take all of your medication as directed even if you think you are better. Do not skip doses or stop your medication early. Avoid antacids, calcium, iron, and zinc products for 2 hours before and 2 hours after taking a dose of this medication. A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time. Talk to your care team about the use of this medication in children. While this medication may be prescribed for children as young as 6 months for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Do not take this medication with any of the following: • Cisapride • Dronedarone • Pimozide • Thioridazine This medication may also interact with the following: • Antacids • Birth control pills • Certain medications for diabetes, like glipizide, glyburide, or insulin • Certain medications that treat or prevent blood clots like warfarin • Didanosine buffered tablets or powder • Multivitamins • NSAIDS, medications for pain and inflammation, like ibuprofen or naproxen • Other medications that prolong the QT interval (cause an abnormal heart rhythm) like dofetilide, ziprasidone • Steroid medications like prednisone or cortisone • Sucralfate • Theophylline

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

Tell your care team if your symptoms do not start to get better or if they get worse. Do not treat diarrhea with over the counter products. Contact your care team if you have diarrhea that lasts more than 2 days or if it is severe and watery. Check with your care team if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medication. This medication may increase blood sugar. Ask your care team if changes in diet or medications are needed if you have diabetes. You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. Do not sit or stand up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. This medication can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Keep out of the reach of children. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep in a tightly closed container. Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.