Emerging therapies for MASH
Transcript
In addition to resmetirom, other therapies are emerging as potential options for the treatment of MASH,
including some off-label treatments. [MUSIC PLAYING]
Pioglitazone, for example, has been shown to improve MASH, but does not significantly reduce fibrosis.
Injectable GLP-1s are also very effective in resolving MASH. In a phase II trial, tirzepatide showed improvement in fibrosis
in more than half of patients without worsening MASH, versus 30% in the placebo group.
Injectable pegozafermin and lanifibranor are also in phase III clinical trials.
liver health
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