What causes pulmonary Langerhans' cell histiocytosis (PLCH)?

Diana Meeks
Diana Meeks on behalf of Sigma Nursing
Family Practitioner
The exact cause of pulmonary Langerhans' cell histiocytosis is unknown, but it's thought that it may be caused by an abnormal immune response. Cells in the lungs appear to react to cigarette smoke, but the means by which this happens is unclear. This reaction in the airways and blood vessels may lead to significant physical damage to the lungs.

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