How effective are opioids at treating migraines?

Donna Hill Howes, RN
Family Practitioner

Guidelines for treating migraine attacks published by the American Headache Society list the following opioids as effective or probably effective: 

  • Effective: butorphanol nasal spray 
  • Probably effective: butorphanol injection, codeine, meperidine, methadone 

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor. 

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