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How effective are opioids at treating migraines?

Donna Hill Howes, RN
Family Practitioner

Guidelines for treating migraine attacks published by the American Headache Society list the following opioids as effective or probably effective: 

  • Effective: butorphanol nasal spray 
  • Probably effective: butorphanol injection, codeine, meperidine, methadone 

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor. 

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.