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What medications can cause delirium?

Audrey K. Chun, MD
Geriatric Medicine
Medications that can cause delirium include:
  • Antihistamines: both those used for colds (e.g., Benadryl, Dimetapp, Chlor-Trimeton), and those used for acid reflux (e.g., Tagamet)
  • Muscle relaxants: Baclofen, cyclobenzaprine
  • Narcotic pain relievers: medications containing codeine, oxycodone and meperidine (Demerol)
  • Benzodiazepines: Xanax, Valium, Ativan, Klonopin, Restoril, Halcion

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.