Can seizure medication affect a man's fertility?

If a man has a normal semen analysis (normal concentration of sperm, normal amount moving and normal shapes of the sperm), it is unlikely that his anti-seizure medication will affect his fertility. If the medicine were affecting his fertility in a substantive way, this would be detected in the semen analysis.

That being said, there is clinical evidence that some medications used to treat epilepsy (such as valproic acid, oxcarbazepine and carbamazepine) might negatively impact hormonal levels in a way that increases sperm morphologic defects.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.