What are the risk factors for coronary artery disease?

Diana Meeks
Diana Meeks on behalf of Sigma Nursing
Family Practitioner

A risk of coronary artery disease can be diagnosed through routine checkups. A blood test can indicate high levels of cholesterol. A check of blood pressure can reveal unhealthy levels. The presence of common symptoms such as chest pain or shortness of breath can also point to the presence of the condition. If any or all of these risk factors are present, further tests of the heart can confirm the diagnosis.

Dr. J J. Marshall, MD
Cardiologist (Heart Specialist)

Some heart disease risk factors are simply part of who we are, and cannot be changed. But many risk factors can be improved by following the treatment prescribed by your doctor and by making healthy lifestyle choices. That means you have the power to reduce your risk of heart disease.

Heart disease risk factors include the following:

  • Age. The risk of cardiovascular disease increases as you age. 
  • Gender. Men are more likely to develop heart disease than women, but that difference begins to disappear after women go through menopause.
  • Family history. Your risk of heart disease is approximately doubled if a parent or a brother or sister developed heart disease early in life.
  • Smoking. When you smoke, you expose your heart and blood vessels to nicotine, carbon monoxide and other harmful substances contained in smoke that can damage blood vessels.
  • High cholesterol levels. High levels of LDL cholesterol—the so-called bad cholesterol—can increase the build-up of plaque in the arteries of the heart. It is also unhealthy to have low levels of HDL, or "good" cholesterol.
  • High blood pressure. If your blood pressure is above 140/90 mmHg for long periods of time, it can damage your blood vessels.
  • Diabetes. High blood sugar levels can damage the blood vessels throughout the body, making it more likely that atherosclerotic plaques will develop.
  • Being overweight or obese. Carrying around too much body weight not only puts a strain on your heart, it also makes it more difficult to control high blood pressure, high cholesterol levels and diabetes.
  • Physical inactivity. A lack of exercise weakens your muscles and makes it harder to control several other heart disease risk factors, including blood pressure, cholesterol levels, diabetes, obesity and stress.
  • Metabolic syndrome. The term metabolic syndrome is used to describe a cluster of traits that, together, increase the risk for developing heart disease. These traits include high blood sugar, high blood pressure, low levels of "good" HDL cholesterol, high blood levels of fats known as triglycerides and excess body weight, particularly in the belly area.
  • Stress. High levels of stress in your life, or a tendency to often feel angry, have also been linked to an increased risk for heart disease.
  • High levels of C-reactive protein. CRP is produced by the body in response to infection or inflammation. If your CRP levels are high, your risk of having a heart attack is increased.

Heart disease is the leading cause of death in American men and women. According to the Centers for Disease Control (CDC), heart disease kills about 600,000 people in the United States each year. Yet, many may continue to underestimate their risk.

Risk factors for heart disease include:

  • your age (55 or older for women)
  • your family history (If your mother or sister had heart disease before age 65 or father or brother had heart disease before age 55, then you are at greater risk for heart disease.)
  • smoking tobacco
  • being sedentary
  • being at an unhealthy weight (more than 20 percent over ideal body weight)
  • having high blood pressure (hypertension), or a blood pressure reading of 140/90 or greater
  • having high LDL (bad) cholesterol: greater than 100 milligrams per deciliter (mg/dL); and/or low HDL (good) cholesterol: less than 50 mg/dL for women or less than 40 mg/dL for men
  • having prediabetes or diabetes

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.