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The keyhole pupil is known as a coloboma. The keyhole is formed by improper fusion of tissues of the eye during the time of development of the baby before birth. The odds of the condition occurring depends on its cause. There are a number of conditions that are associated with the formation of a coloboma. If it is a condition that runs in the family, the odds can be as high as 50/50 that another child in the family may be born with the condition.
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