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What are SGLT2 inhibitors?

Donna Hill Howes, RN
Family Practitioner

SGLT2 (sodium-dependent glucose co-transporter 2) inhibitors lower blood sugar by helping the kidneys remove it from the body in the urine. They are taken by mouth. SGLT2 inhibitors include canagliflozin (Invokana), dapagliflozin (Farxiga), and empagliflozin (Jardiance). Invokamet, Xigduo, and Synjardy are combinations with metformin. Glyxambi combines empagliflozin and linagliptin. 

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor. 

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