How does heparin interact with other medications or foods?

Heparin interacts with a number of medications, including aspirin and ibuprofen. Those medications should only be taken with heparin with your doctor's permission. Other medications that may increase or decrease the effectiveness of heparin include: antihistamines; digoxin; tetracyclines; injectable cephalosporins; injectable and certain antidepressants. Also, the nicotine found in cigarettes can reduce the effectiveness of heparin. Tell your doctor if you smoke before beginning treatment. If you stop smoking, tell your doctor so that your dosage can be adjusted.

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