Anticoagulant

Anticoagulant

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    A , Pharmacy, answered

    The manufacturer of this drug has withdrawn it from the market, and it is not currently available.

    Drotrecogin alfa is a recombinant form of human activated protein C, a natural anticoagulant enzyme with potent anti-clot and anti-inflammatory properties. It is administered to hospitalized adults with severe sepsis and multiple organ system failures to decrease the mortality rate. Sepsis is a bacterial infection in the bloodstream that affects the whole body by causing inflamation and clot formation in various organs. Drotrecogin alpha works by decreasing the production of inflammatory chemicals, preventing clot formation and increasing clot breakdown. This drug is given slowly by continuous intravenous infusion and may take as long as four days to administer.  Drotrecogin alfa is available only under the brand name Xigris.

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    A , Pharmacy, answered
    Fragmin is the brand name of dalteparin. It is an anticoagulant, which prevents dangerous blood clots by thinning the blood. Dalteparin is often taken with aspirin to prevent blood vessel complications in patients with angina (chest pain) or heart attacks. Dalteparin is also used to prevent a type of blood clot called deep vein thrombosis (DVT), which can lead to blood clots in the lungs (pulmonary embolism). A DVT can occur after certain types of surgery, or in people who are bedridden due to a long-term illness. Dalteparin is also used long term to treat a blood clot called a venous thromboembolism.

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    A , Pharmacy, answered
    Dalteparin is the name of the active ingredient in a drug sold under the brand name Fragmin. It is an injectable anticoagulant; it prevents dangerous blood clots from forming. In other words, this is a drug that "thins the blood." Dalteparin is often taken with aspirin. This combination prevents clotting problems in blood vessels. It’s effective for treating deep vein thrombosis. This is a serious blood clot that can occur after surgery, when someone is bed-ridden for a long-term illness, or is sitting and not mobile during long car rides or plane flights. It also treats heart attacks and angina (chest pain).

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    Side effects of Innohep can occur. Discomfort at the injection site is common, and need only be reported to your doctor if it is severe or if it is accompanied by bleeding. More serious side effects are possible and you should contact your doctor right away if you experience them. These include symptoms of an allergic reaction to Innohep, including severe itching, a rash or hives, swelling of the face or mouth and trouble breathing. Other serious side effects include:

    • faintness
    • dizziness
    • lightheadedness
    • fever
    • headaches
    • constipation
    • nausea and vomiting
    • chest pain
    • urinary tract infection
    • unusually heavy menstrual flow

    Since this drug can cause bleeding, be aware of side effects that would indicate bleeding problems, such as:

    • nosebleeds
    • bruising
    • bleeding gums
    • red skin spots
    • black stools
    • coughing blood
    • bloody urine
    • back and stomach pain

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    A , Pharmacy, answered
    Innohep is the brand name for the drug tinzaparin, classified as a low molecular weight heparin. It is an anticoagulant used to treat blood clots. This medicine is administered by injection, often in a medical facility.

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    A , Pharmacy, answered

    Innohep may cause problems for people with certain other health conditions. These include:

    • bleeding disorders
    • intestinal bleeding or ulcers
    • stomach bleeding or ulcers
    • bleeding of the brain
    • hemophilia
    • liver disease
    • bowel disease
    • aneurism
    • certain heart infections
    • kidney disease
    • high blood pressure
    • diabetic retinopathy
    • those who have previously suffered a stroke or a negative reaction to heparin

    People who have recently given birth or had surgery on their eye, spine or brain may not be able to receive this medication. Although this medicine is pregnancy Category B, it does contain benzyl alcohol, a preservative that is harmful for premature babies. If you are pregnant or breastfeeding, you should check with your doctor to see if this drug is safe enough for use. In addition, this drug can cause side effects, including an allergic reaction. Before you receive it, you should be aware of the possible side effects and what to do if they occur.

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    A , Pharmacy, answered

    Innohep should not be given with aspirin, drugs related to aspirin, blood thinners, mifepristone or other blood clot medications. It also may interact with:

    • nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen
    • some heart attack medications
    • clopidogrel
    • dextran
    • dipyridamole
    • sulfinpyrazone
    • ticlopidine
    • tromethamine
    • dasatinib
    • ibritumomab
    • pentosan
    • pentoxifylline
    • tositumomab
    • tirofiban

    Make sure you tell your doctor about all of the other medications, vitamins and herbal supplements you take. Your doctor can determine whether or not these may produce harmful side effects when combined with Innohep.

  • 1 Answer
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    A , Pharmacy, answered
    People who are allergic to Innohep, pork, benzyl alcohol, sulfites or any ingredient in this medication should not use it. People who have had low platelets due to heparin drugs, a condition called heparin-induced thrombocytopenia (HIT), should not use this medication. In addition, people with significant, ongoing bleeding or kidney disease, those older than 90, and pregnant women may not be able to take this medication.

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    A , Pharmacy, answered

    Dalteparin is a type of medication called an anticoagulant or blood thinner. It prevents the formation of blood clots in people who have had certain surgeries, chest pains (angina) or heart attacks. It can prevent a condition called deep vein thrombosis (DVT), in which a blood clot forms in the large veins of the legs after surgery. By preventing DVT, dalteparin reduces a person's risk of a life-threatening pulmonary embolism, in which a blood clot travels to the lungs and damages lung tissue.

    Dalteparin treatment also can benefit people with cancer who are at a higher risk of developing a type of blood clot called venous thromboembolism (VTE). Dalteparin can be categorized as a low molecular weight heparin. While it cannot dissolve an existing blood clot, dalteparin can prevent an existing clot from getting larger, as well as preventing new blood clots from forming. Dalteparin is administered intravenously and is often paired with other medications such as aspirin. The brand name of dalteparin is Fragmin.

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    A , Pharmacy, answered

    Dalteparin may cause a number of side effects. Get emergency medical attention if you experience signs of an allergic reaction, such as hives, itchy skin rash, difficulty breathing or swelling of the face, tongue or throat. Discontinue treatment and talk to your doctor as soon as possible if you experience any of the following severe side effects: easy bruising or bleeding that will not stop; bloody, black or tarry stools; pink or red urine; difficulty walking; severe or persistent dizziness or fainting; numbness or tingling in the feet or legs; muscle weakness; red or brown vomit that resembles coffee grounds; unusually heavy menstrual periods; or feverish symptoms.

    Dalteparin also may cause more common side effects that do not require medical attention unless they worsen or persist. Call your doctor if the following mild side effects become bothersome: pain, swelling, redness at the injection site or upset stomach. During dalteparin treatment, tell your doctor if you experience any side effects that are not listed here.