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When should I call my doctor if I am taking Percodan?

If you are taking Percodan, a prescription pain reliever that is a combination of oxycodone and aspirin, call your doctor immediately if you experience any of these side effects:
  • a rash or hives, swelling of your face, lips, tongue, eyes, lower legs, ankles, feet or hands or trouble breathing (these may be signs of an allergic reaction that requires emergency medical help)
  • black-colored bowel movements
  • changes in your eyesight
  • chest pain
  • trouble swallowing
  • hoarseness
  • fainting or loss of consciousness
  • hallucinations
  • difficulty urinating or changes in urination
  • fatigue
  • fast heartbeat
  • mental confusion
  • fever, chills, aches and pains
  • light-headedness
  • seizures
  • bleeding or bruising
Other more common side effects of Percodan do not typically require treatment unless they are severe or don't go away. They include:
  • constipation (call your doctor if you do not have a bowel movement for three days)
  • dizziness
  • drowsiness
  • dry mouth
  • headache
  • nausea
  • vomiting
  • loss of appetite
  • depression
  • itching
  • sweating
Oxycodone, a component of Percodan, can be habit-forming. Avoid taking a larger dose than directed or taking it more frequently or for a longer period of time than directed. If your body becomes used to this medicine, you may need a higher dose for pain relief. If this happens, ask your doctor about adjusting your dosage. Also call your doctor if you have been taking this medication regularly and wish to stop. Your doctor will probably want to reduce your dose gradually to prevent withdrawal symptoms, such as sweating, chills, irritability, anxiety, muscles aches and diarrhea.