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What are the side effects of hydrocodone and acetaminophen?

Common side effects of hydrocodone-acetaminophen include: dizziness, lightheadedness, drowsiness or sedation and nausea and vomiting, belching; mood swings; loss of appetite; constipation; fear or nervousness; and indigestion. If these persist, call your doctor.

Other less common and more serious side effects that need medical attention include: hearing loss; difficulty hearing; back pains; leg pains; stomach pains; black, tarry stools; bleeding gums; blue lips or skin; fever or chills; choking, cough or hoarseness; dark urine, decreased urine output or frequency, difficult or painful urination; dizziness; rapid heartbeat; edema; tiredness or weakness; headaches; light-colored stools; nosebleeds; pale or bluish fingernails; pinpoint red spots on the skin; unable to speak; unusual bleeding or bruising; upper right abdominal or pain; wheezing; and yellow eyes and skin (jaundice).

Sympoms of allergic reactions may include: hives, itching; difficulty breathing; puffiness or swelling of the eyelids or around the eyes, face, lips or tongue; tightness in the chest; and difficulty swallowing. An allergic reaction is a medical emergency.

An overdose can occur with this medication if prescribed doses are not followed. Contact your doctor immediately if any symptoms of overdose appear. They include: bloody or cloudy urine; lapsing of consciousness; chest pain or discomfort; cold and clammy skin; decreased awareness or responsiveness; general discomfort or feeling of illness; increased sweating; slow or irregular heartbeat; lightheadedness; dizziness or fainting; sudden decrease in urine output; unpleasant breath odor; or vomiting blood.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.