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How can I minimize the side effects of Xodol?

To minimize the side effects of Xodol (hydrocodone and acetaminophen), a drug prescribed to relieve moderate to moderately severe pain, you should:
  • Tell your doctor if you have ever had an allergic reaction to any drug, especially other opiate drugs such as morphine or codeine. Do this before you begin taking Xodol.
  • Give your doctor and pharmacist a list of all your other medicines (prescription and nonprescription) and dietary and herbal supplements before you begin taking Xodol. Be especially careful to mention if you take antidepressants, antihistamines, antianxiety or antipsychotic medications or other narcotic drugs. Once you start taking Xodol, do not take any new medicines or supplements without checking with your doctor or pharmacist first. 
  • Give your doctor a detailed medical history, including not just medical problems you have currently but also those you had in the past. Be especially careful to mention if you have ever had breathing problems, a head injury, trouble urinating normally, Addison's disease, glaucoma or problems with your lungs, liver, kidneys or thyroid gland.
  • Take Xodol exactly as your doctor tells you to. Do not take more than is prescribed or take it for a longer period of time than your doctor recommends. 
  • Keep your medical appointments. Your doctor may want to monitor you carefully while you take Xodol.
  • Do not take any other medicines that contain acetaminophen if you are taking Xodol. 
  • Do not drink alcohol while you are taking Xodol. 
  • Tell your doctor if you have had surgery in the past or have surgery (including dental surgery) scheduled for the near future. 
  • Avoid becoming pregnant. It's possible that Xodol could harm a developing fetus. 
  • Avoid breastfeeding. It's possible that Xodol could pass into breast milk and harm a nursing infant.
  • Do not drive a car or operate machinery until you know how Xodol affects you. Xodol can cause dizziness and drowsiness as well as other symptoms.
Call your doctor if you experience the following side effects from Xodol, especially if they are severe or persistent.
  • sleepiness and/or lethargy
  • mental health symptoms such as cloudy thinking, anxiety, fear, feeling uneasy or unwell
  • constipation
  • trouble urinating or urinating completely
  • skin rash or itching
  • blood test abnormalities -- low platelet or white blood cell count
Call your doctor immediately if you accidentally take too much Xodol -- do not wait until you experience symptoms.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.