What to know about screening for lung cancer

Screening for lung cancer can help catch the disease early—and it could save your life.

Updated on September 18, 2025.

Lung cancer is very common, accounting for about one-fifth of cancer deaths in the United States. Up to 90 percent of lung cancer cases are due to smoking.

“Lung cancer is the most common cancer worldwide,” says Matthew Arneson, MD, a cardiac and thoracic surgeon in Wichita, Kansas.

Lung cancer is often diagnosed when it is more advanced. That can make it harder to treat and contributes to low five-year survival rates (the percentage of people who are alive five years after being diagnosed with a certain medical condition). More than half of people with lung cancer survive longer than five years if their cancer hasn’t spread at the time it was diagnosed. The five-year survival rate for all cases of lung cancer, including those that have spread, is about 1 in 4.

Only about one-quarter of people with lung cancer are diagnosed at an early stage. “Our goal is to increase [that number] so we can treat them earlier and have a better cure rate,” Says Dr. Arneson.

Lung cancer screening may help to identify the disease at earlier stages. Here's what to know about it.

Should you be screened?

According to guidelines issued by the U.S. Preventive Services Task Force (USPSTF) in March 2021, you should get screened annually for lung cancer if you’re between the ages of 50 and 80 and you:

  • Smoke cigarettes currently or have quit smoking within the past 15 years
  • Have a 20 pack-year smoking history

A “pack-year” is a measure of how much a person has smoked in their lifetime. It’s calculated by taking the number of packs they smoke per day times the number of years they smoked. So, if you’ve smoked one pack a day for 20 years, or two packs a day for 10 years, you fit the criteria.

A low-dose computed tomography (CT) scan is the only reliable screening method for lung cancer, says Arneson. CT scans use low-dose X-rays and a computer to take detailed pictures of the inside of your body. Other tests that have been used in the past include sputum tests, which look for cancer cells in your saliva, and chest X-rays.

“CT scans are a lot more specific,” says Arneson. “With a chest X-ray, you often can’t see nodules [irregular growths of tissue] that are close to the heart or other organs. The other thing is, some nodules are very small and the X-ray is not as sensitive [accurate at identifying disease] in finding small nodules. The smaller the nodule, the more likely it is to be cured.”

Benefits and risks

The benefit of lung cancer screening is that it can help detect small growths early. Earlier detection of lung cancer can help you start treatment earlier, when it may work better, rather than if you waited for symptoms to appear. Symptoms of lung cancer can include coughing up blood, pain, shortness of breath, and weight loss.

“Unfortunately, when symptoms arise, it means the cancer has advanced,” says Arneson.

The risks of screening are few, according to Arneson. “Low-dose” CT scans do expose you to a low level of radiation, according to the USPSTF. But the amount of radiation used for low-dose CT scans is about the same, and sometimes less than, the background radiation from the environment an average person in the U.S. is exposed to over the course of a year.

Another risk is the potential for false positives. This is when screening shows something that looks like lung cancer, and further testing shows it is not actually cancer. While the rate of false positives can be high in lung cancer screening, it is still an important tool in early detection.

“That’s why before anyone gets a CT scan, there’s a conversation about options and the risks of false positives and negatives,” says Arneson. “No test is 100 percent accurate.”

Talk to your HCP if you’re a current or former smoker between ages 50 and 80 to see if screening is right for you, and ask how your insurance may help cover costs.

Article sources open article sources

Centers for Disease Control and Prevention. Lung Cancer Risk Factors. February 13, 2025.
American Cancer Society. Annual Cancer Facts and Figures. Accessed September 18, 2025.
American Cancer Society. Cancer Facts and Figures 2025. 2025.
American Lung Association. State of Lung Cancer: Key Findings. November 13, 2024.
U.S. Preventive Services Task Force. Lung Cancer: Screening. March 9, 2021.
American Cancer Society. How to Detect Lung Cancer. January 29, 2024.
National Cancer Institute. Lung Cancer Screening (PDQ)–Health Professional Version. April 17, 2025.

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