Do Some Parkinson's Meds Have a Timeframe Where They Stop Working?

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You're talking about the drive the main stage drive for Parkinson's disease which is levidopa. Levidopa is converted into dopamine and it's not quite that the drug stops working, its just that with regulation of the system and with long term Parkinson's disease coupled with that medication, the brain starts to change in a way that the medicine doesn't work as well, so you have to jerk up the dose, and then it works for a while, and then it stops working as well.

Eventually you have to jerk up the dose to where the therapeutic is so small. You're taking it multiple times a day with maybe just a little bit of benefit and that drug also tends to cause a condition called discinesia which is the wiggles, patients that move involuntarily when their dose is probably at its peak and with prolonged use of that drug in relatively high doses it can set you up for these [xx] complications.