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Virtual anatomy: atopic dermatitis

Updated on October 22, 2024

Atopic dermatitis (AD) is a chronic, inflammatory disease of the skin. Join your host, Kimberly, to explore the pain and suffering brought on by AD.

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Transcript

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[MUSIC PLAYING]
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Separating the tissues in the human body from the dangers lurking outside of it is the skin, a living, breathing, 16-
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to 22-square-foot organ meant to protect and shield us from harm, an organ that for over 16 million American adults is
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a site of pain and suffering in the form of atopic dermatitis, a type of chronic, relapsing, inflammatory skin disease set
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on damaging the defensive barrier that keeps us whole. Hi, I'm Kimberly, your virtual anatomy host.
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And in this segment, we will explore the fascinating world of the skin. To show it working in perfect harmony, how that harmony can
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be disrupted by atopic dermatitis, and reasons to restore the balance before the disease gets out of control, let's dive deeper.
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At first glance, the skin appears calmingly mundane, almost devoid of any remarkable landmarks that would excite a nomadic traveler.
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Dune-like land forms on the outermost layer, the epidermis, stretching and rolling over every crevice of the body,
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seemingly barren yet housing a vibrant, bustling world that permeates the skin with life.
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Underneath the epidermis, we find the crowded, densely-packed dermis, sourced with oxygen and nutrient-rich blood vessels,
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pain-receptive and touch-sensing nerves, and glands that help support healthy skin.
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Dropping below the dermis, a thickly padded, insulated floor of the hypodermis. All three unify together as the body's largest organ.
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Underneath the smooth surface of skin exists a microscopic alien-like sea of cells, working together
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in choreographic sequence to maintain the erected wall designed to keep us in balance.
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In atopic dermatitis, this delicate dance appears abnormal and uncoordinated.
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The overly sensitive skin barrier, flawed in composition, cells misguided and hyperactively angry
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at the lack of flow and synchronicity, ready to attack and erode the very organ keeping them safe.
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On our way back to the surface, we find the once unified and harmonized skin in the midst of an atopic dermatitis flare up.
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The soft, silky, rolling dunes interrupted by itchy, mound-like bumps sprouting in every direction.
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Raw, oozing blisters stripping the frontline defenses of their protective shield. Flakes and crusts of skin barely hanging on to inflamed patches.
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A treatment once strong enough to keep flare-ups at bay, overpowered by the disease.
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Over time, cycles of injury and repair can damage the skin permanently, remodeling a once fruitful environment into a near uninhabitable landscape,
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vulnerable to infections and germs. A constant reminder of lost battles against atopic dermatitis and medications not working
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as well as they should. Fortunately, newer treatments can restore much needed balance, calm down
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the avalanche of misguided cells, help skin rebuild its protective barrier, and make the painful symptoms of atopic dermatitis,
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like itchiness and inflammation, a thing of the past. Ask your doctor about newer and more effective
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treatment options. And let's put atopic dermatitis to rest.

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