Vitamin K

Vitamin K

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  • 1 Answer
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    A , Pharmacy, answered
    Injections of vitamin K1 are used to treat problems with blood clotting related to vitamin K deficiency. These deficiencies can occur in newborns or can result from various disorders caused by medication side effects. Aqueous solution of vitamin K1 is usually administered in a hospital setting, under a doctor's prescription and instructions.

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    A , Pharmacy, answered
    Injections of vitamin K1 (as an aqueous colloidal solution) do not generally interact with other drugs. However, these injections can temporarily decrease the effectiveness of certain anticoagulants. This effect can usually be offset by either adjusting the anticoagulant dose or substituting a different anticoagulant.

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    A , Pharmacy, answered
    People who are not deficient in vitamin K or who are allergic to any injection ingredients should NOT receive vitamin K1 injections. It is not clear whether vitamin K1 injection is appropriate for pregnant mothers, breastfeeding women and children. Because injectable vitamin K1 can accumulate rapidly in the body (presenting a risk of overdose), these injections should be given only after other approaches have been exhausted. Care should always be taken to limit dosage.

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    A , Pharmacy, answered
    Aqueous colloidal solution of vitamin K1 is associated with the following side effects:
    • unusual taste in the mouth, unusual skin sensations, discolored skin, dizziness, compromised pulse, sweating, low blood pressure and problems breathing
    • allergic reactions (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives)
    In addition, when delivered intramuscularly or intravenously, the rapid accumulation of vitamin K in the body can lead to an overdose that interferes with basic bodily functions. In these cases, cardiac or respiratory failure can lead to death.

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    A , Pharmacy, answered
    Before receiving an injection of an aqueous colloidal solution of vitamin K1, you should know that:
    • Intramuscular and intravenous injections of vitamin K1 have been associated with deaths, caused when a rapid buildup of vitamin K1 in the body leads to cardiac or respiratory failure. 
    • Because of the risk of death, aqueous colloidal solution of vitamin K1 should be administered only in an emergency situation where other delivery mechanisms are not possible.
    • Some vitamin K1 solutions may contain toxic quantities of aluminum.
    • While vitamin K1 injections can be given to newborns, solutions containing benzyl alcohol can be dangerous for them.
  • 1 Answer
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    A , Pharmacy, answered
    Phytonadione is a synthetic form of vitamin K used to treat and prevent both blood clotting issues and vitamin K deficiency. Brand names for phytonadione include Mephyton and Vitamin K1.
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    A , Pharmacy, answered

    There are several risks associated with taking vitamin K1:

    • The injectable may contain aluminum and benzyl alcohol, both of which should not be used in newborns
    • It takes one to two hours for injectable vitamin K1 to work
    • It takes up to six to 12 hours for the oral vitamin K1 to work
    • It will not reverse the anti-clotting action of heparin
    • Repeated use of vitamin K1 is dangerous in people with liver disease

    If you have any questions, ask your doctor.

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    A , Pharmacy, answered
    If you are allergic to phytonadione or any ingredient used to make it, you should not take this drug. For example, some forms may contain the ingredient polysorbate 80; if you know you are allergic to this substance, ask your doctor if the formulation you will take contains this. Some of the injectable preparations of phytonadione contain aluminum; talk to your doctor if this is a concern.

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    A , Pharmacy, answered
    Although phytonadione is a vitamin -- vitamin K -- it is not available without a prescription from your doctor. If you think you may need vitamin K, discuss this concern with your doctor. Your doctor can do several tests on your blood to determine whether your blood is clotting normally and whether vitamin K would help you.
     
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    A , Pharmacy, answered
    A serious, but rare, effect of phytonadione (vitamin K) is anaphylaxis. This is a severe allergic response to phytonadione in which your body's immune system treats the vitamin K as a harmful, rather than helpful, substance. This causes the release of many chemicals that can damage organs throughout your body. Low blood pressure, difficulty breathing, or even a total stop in breathing are all indications that you are having an anaphylactic reaction to phytonadione.