How does vitamin B3 interact with other medications?


Among the drugs and supplements that may interact with vitamin B3 (niacin) supplements are:

  • warfarin
  • doxazosin
  • terazosin
  • isosorbid
  • prazosin
  • nitroglycerin
  • multivitamins that contain niacin
  • amlodipine
  • verapamil
  • diltiazem
  • nisoldipine
  • felodipine
  • nimodipine
  • nicardipine
  • nifedipine
  • atorvastatin
  • simvastatin
  • fluvastatin
  • pravastatin
  • lovastatin

Take some cholesterol medications (colestipol and cholestyramine) at least four hours before or after taking vitamin B3. The vitamin can also raise blood sugar, so if you're diabetic talk to your doctor about adjusting your doses of insulin and other medications. Taking a nonsteroidal anti-inflammatory a half hour before taking your dose of vitamin B3 may help prevent flushing, a common side effect.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.