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How does vitamin B12 help the brain?

Nutritional support for the methylation cycle is an area in which nutrition plays a critical role in fighting depression. The methylation cycle is essential for mental and physical health. It is critical to the metabolism of catecholamines in the synapse via an enzyme (COMT) as well as the synthesis of "depression-relevant" compounds such as melatonin, myelin basic protein, carnitine, CoQ10, etc.

Basic nutrients necessary for normal function of this cycle include vitamin B12, glycine, serine, activated B6, selenium, cysteine, methionine and folic acid.

One of the critical ingredients for the methylation cycle is B12. Vitamin B12 plays a vital role in the metabolism of fatty acids essential for the maintenance of myelin in the brain.
Vitamin B12 is involved in the function and development of the brain, nerve cells, the myelin sheaths that protect nerves, and blood cells. Vitamin B12 is sometimes taken to treat memory loss, poor concentration, and Alzheimer’s disease and to boost your mood or energy levels. Deficiencies in B12 can make your body unable to produce the protective myelin and can lead to nerve damage, cognitive problems and memory loss.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.