How long do human papillomavirus (HPV) vaccines protect against infection?

 Dr. Diane Harper
Health Education

Like many vaccines, the human papillomavirus (HPV) vaccine doesn't last a lifetime. Learn how long you can expect to be protected with the HPV shot by watching this video.

The duration of immunity is not yet known. Research is being conducted to find out how long protection will last. Phase III clinical trials have shown that Gardasil and Cervarix can provide protection against HPV16 for 4 years. Smaller studies have suggested that protection is likely to last for longer than 4 years, but it is not known if protection conferred through vaccination will be life long.

This answer is based on source information from the National Cancer Institute.