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What is Lonsurf?

Lonsurf is a combination of two drugs, trifluridine and tipiracil, in a single tablet, for the treatment of metastatic colorectal cancer. The two drugs interfere with the growth of cancer cells. Lonsurf is intended for patients whose cancer of the colon and/or rectum have spread to other parts of the body (metastacized) and who have failed to be helped by other chemotherapy treatments. It should be taken twice a day, within an hour after breakfast and dinner, over a 28-day cycle (taken on days 1-5 and days 8-12). Lonsurf can cause fetal harm and is only advised for pregnant women if necessary. Women should not breastfeed while taking Lonsurf. Common side effects include weakness, fatigue, anemia, poor appetitie, nausea, vomiting, diarrhea, stomach pain, fever, and an increased chance of infection. Doctors will monitor blood of patients closely to watch for lower white blood cell and red blood cell counts, which cause several of these side effects. 

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.