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What is the treatment for castration-resistant prostate cancer?

Castration-resistant prostate cancer (or CRPC) is a recent name given to cancers that grow after initial hormone therapies in the category known as LHRH agonists (for instance, leuprolide or goserelin) or after surgical castration. It used to be called hormone-refractory prostate cancer (or HRPC) but this name was felt to be misleading since patients may still respond to additional hormone treatments after having cancer progression on LHRH agonists or surgical castration. 

Many treatment options exist for CRPC, which is good news. In fact, there are now at least 7 FDA-approved treatments:

  1. Mitoxantrone (Novantrone)
  2. Docetaxel (Taxotere)
  3. Cabazitaxel (Jevtana)
  4. Sipuleucel T (Provenge)
  5. Abiraterone Acetate (Zytiga)
  6. Zoledronic Acid (Zometa)
  7. Denosumab (Xgeva)

And more to come in the near future!

Chemotherapy is the treatment for castration-resistant prostate cancer.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.