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Who should not take Jakafi?

Pregnant women or women who plan on becoming pregnant should not take Jakafi (ruxolitinib) without first discussing the risks and benefits of the drug with a doctor. Scientists haven't done enough studies to know if the medication, which is given for the bone marrow disease myelofibrosis, is safe if taken during pregnancy.

Breastfeeding women and people with severe kidney or liver disease should not take Jakafi.

Jakafi hasn't been adequately tested in children, so scientists don't know if it's safe or effective for them. Talk with your child's doctor about possible risks.

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