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Phobia induced panic responds preferentially to alprazolam (Xanax), and benzodiazepines such as clonazepam (Klonopin), since these medications work on the anxiety (raphe nucleus), GABA and glutamate receptors, and the norepinephrine induced terror (locus coeruleus). Beta blockers (e.g. propranolol [Inderal]) block the physical symptoms of panic very quickly, but have no effect on the cognitive experience. They can be very useful for specific situations (e.g. public speaking), or with other forms of panic. Cognitive therapy and behavioral exposure should be effective in this group. Buspirone (Buspar) works on the serotonin neurons in the raphe nucleus to reduce anticipatory anxiety, but does not have any effect on the norepinephrine induced terror (locus coeruleus).
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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.