Is it possible to overdose on Subutex?

It is possible to overdose on Subutex (buprenorphine), but it's relatively unlikely. Subutex helps treat addiction to opioids, including heroin, morphine and other narcotic painkillers. It helps people break their addictions by preventing or stopping withdrawal symptoms and by blocking the "high" feeling that people can get from opioid drugs.

However, Subutex does itself contain a semisynthetic opioid, so overdoses are possible -- particularly if you combine it with another drug that depresses the central nervous system (CNS). Other CNS depressants include tranquilizers, sedatives, some painkillers, sleeping pills, antianxiety drugs, antidepressants and antihistamines. Combining Subutex with one of these drugs could dangerously slow your breathing. It could even be fatal.

Before you start Subutex, give your doctor and pharmacist a list of all your other medications (prescription and nonprescription) and dietary and herbal supplements. Once you're on Subutex, do not take any new drug or supplement without consulting your doctor and pharmacist first.

Take Subutex exactly as your doctor tells you. Do not take more or less or take it more or less frequently than prescribed. Never inject Subutex.

If you do think you have taken too much Subutex, or if you have consumed alcohol or a CNS depressant in addition to Subutex, call your doctor or 911 right away. Also call 911 if you experience any of the following symptoms, which could signal an overdose:
  • extreme drowsiness
  • dizziness
  • blurred vision
  • slowed breathing
  • pinpoint pupils
  • low blood pressure

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.