How soon after taking methadone will my symptoms improve?

If you use methadone for pain relief, your symptoms will improve within a very short time of taking this medication and last from 4 to 8 hours. However, effectiveness and longevity may change if you have built up a tolerance to opiates. If you are using methadone to treat addiction to other narcotics, the results are more variable, depending on tolerance levels and how much of another drug you have in your system. Withdrawal symptoms are usually alleviated within 2 to 4 hours of initial treatment with methadone. A government-treatment program will monitor you and adjust your dosage so that you can eventually control symptoms for 24 hours at a time.

Continue Learning about Opiate Agonists

What medications can cause breathing problems when taken with opioids?
Travis M. Hendry, MDTravis M. Hendry, MD
Medications that interact with opioids to decrease breathing include clonazepam (Klonopin), alpr...
More Answers
How do you treat constipation and other side effects of taking opioids?
Devi E. Nampiaparampil, MDDevi E. Nampiaparampil, MD
Your doctor may prescribe a stool softener along with an opioid to prevent constipation. Other commo...
More Answers
How do opioids relieve pain?
James P. Ioli, DPMJames P. Ioli, DPM
Prescription drugs that contain opioids (opioid analgesics) such as codeine are useful for pain ...
More Answers
What are the side effects of opioid medication for short-term pain?
Travis M. Hendry, MDTravis M. Hendry, MD
Opioid medication (strong medications that affect the way your brain handles pain signals) for s...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.