Advertisement

What is celecoxib?

Dr. Scott D. Martin, MD
Orthopedic Surgeon
Celecoxib (Celebrex) is in a class of prescription non-steroidal anti-inflammatory drugs (NSAIDs) known as COX-2 inhibitors, which relieve pain with less stomach irritation than traditional NSAIDs. Concerns about cardiovascular side effects mean it should be used only in cases in which a patient does not have heart disease, has tried other pain relievers without success, and may be prescribed when patients must take concomitant blood thinners (anticoagulants such as warfarin).
Donna Hill Howes, RN
Family Practitioner

Celecoxib (Celebrex) is a type of nonsteroidal anti-inflammatory drug (NSAID) called a COX-2 inhibitor. These drugs have fewer side effects than traditional NSAIDs. Celecoxib can help reduce the pain of osteoarthritis. It does not slow the progress or reverse the course of the disease. It is an option for people who are at risk for digestive complications from traditional NSAIDs.

Some treatment guidelines recommend that people who take a COX-2 inhibitor for osteoarthritis should also take a proton pump inhibitor, such as omeprazole (Prilosec), to protect their digestive system. This is especially true for people who are at risk for digestive damage, such as older adults and those who have had ulcers, GI bleeding, or other digestive problems in the past. 

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor. 

Continue Learning about Nonsteroidal Anti-inflammatory Drugs

An Alarming Side Effect of NSAIDs: Ovulation Stops
An Alarming Side Effect of NSAIDs: Ovulation Stops
If the Duchess of Cambridge (Kate Middleton) had been taking any of the three common NSAIDs mentioned below, for any of the aches and pains that accom...
Read More
Can NSAIDs and acetaminophen be combined?
Stacy Wiegman, PharmDStacy Wiegman, PharmD
NSAIDs and acetaminophen are sometimes combined to form a stronger medication than if each medicatio...
More Answers
What are side effects of nonsteroidal anti-inflammatory drugs (NSAIDs)?
Dr. Darria Long Gillespie, MDDr. Darria Long Gillespie, MD
NSAIDs can have serious side effects on the digestive system and are usually not recommended for con...
More Answers
Are Steroid Injections for Back Pain Safe?
Are Steroid Injections for Back Pain Safe?

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.