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What are COX-2 inhibitors?

Christopher Chiodo, MD
Orthopedic Surgery
A type of prescription nonsteroidal anti-inflammatory drugs (NSAID) known as a COX-2 inhibitor, such as celecoxib (Celebrex), relieves pain and inflammation and may reduce the risk for gastric ulcers and bleeding, which sometimes make older NSAIDs difficult to tolerate. COX-2 inhibitors have their own side effects, though, so discuss your personal health risks with your doctor when considering the long-term use of these medications.
COX-2 inhibitors are medications used for headaches and muscle pain.  COX-2 inhibitors are similar to NSAIDs in that they reduce inflammation.  Reducing inflammation leads to pain relief for muscle pains or headaches.  For many people, COX-2 inhibitors don’t cause as much stomach upset as NSAIDs, so they are better tolerated.  However, both COX-2 inhibitors and NSAIDs have cardiovascular risks even in people with no history of cardiac disease.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.