Treximet tablets, active ingredients of sumatriptan and naproxen sodium, can cause minor side effects including gastrointestinal upset like nausea, constipation or diarrhea. Some people experience heart palpitations, dizziness or unusual sensations, like muscle tightness, heat or tingling on the skin.
Naproxen is a non-steroidal anti-inflammatory drug (NSAID), which can cause more severe side effects in some people. These can include an allergic reaction, which could cause hives, trouble breathing or swollen tongue or mouth.
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