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Does Celebrex (celecoxib) help osteoarthritis pain?

Stacy Wiegman, PharmD
Pharmacy Specialist

Celebrex (celecoxib) does help osteoarthritis pain, as well as swelling, stiffness and joint tenderness. Osteoarthritis occurs when the cartilage that supports and cushions the joints of the hands, spine, hips and knees wears away, causing bones to rub against each other.

As the cartilage becomes increasingly damaged, chemicals called prostaglandins are released, which cause nerve endings to send pain signals to the brain. Celebrex, a prescription nonsteroidal anti-inflammatory drug (NSAID) called a COX-2 inhibitor, stops prostaglandin production to reduce pain. Celebrex can cause serious side effects, including an increased risk for a heart attack.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.