The precise cause of stage 1 non-Hodgkin lymphoma remains a mystery. The disease starts when white blood cells called lymphocytes, continue to reproduce rather than dying off to be replaced by new cells. Lymphocytes are produced in the lymphatic system and are normally used by your body to fight off germs and infections. The disease usually affects a specific type of lymphocyte called B cells; more rarely, it affects another type called T cells. Some varieties of the disease have been linked to viruses.
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