Who should not take Benadryl?

Benadryl should not be taken by anyone with a known allergy to any ingredient in the product.  Benadryl may not be appropriate for everyone due to the potential interaction with a variety of medications, side effects and risks related to other medical conditions. Benadryl may not be right for you if you have these conditions:

  • glaucoma
  • ulcers
  • gastroesophageal reflux disorder
  • diabetes
  • persistent cough or cough with mucus
  • enlarged prostate
  • asthma
  • hyperthyroid disease
  • diseases of the heart
  • hypertension
  • chronic obstructive pulmonary disease

If you are currently taking or recently stopped taking a monoamine oxidase inhibitor (MAOI), you should talk to your doctor prior to taking Benadryl. Benadryl should never be used for the purpose of sedation in children.

Continue Learning about Nasal Agent

Can decongestants relieve allergy symptoms?
Retreat Doctors’ Hospital - HCA VirginiaRetreat Doctors’ Hospital - HCA Virginia
Over-the-counter decongestants may be helpful in treating the stuffy noses that often go along with ...
More Answers
What should I know before taking cromolyn?
Donna Hill Howes, RNDonna Hill Howes, RN
It is not known if cromolyn is safe or effective for children and adolescents under 18 years of age....
More Answers
Can I overdose on Benadryl?
Dr. Michael Roizen, MDDr. Michael Roizen, MD
Yes! As with many medicines, both prescription and over-the-counter, it is possible to overdose on B...
More Answers
How do antihistamines relieve allergy and sinus symptoms?
Dr. Jeanne Morrison, PhDDr. Jeanne Morrison, PhD
Antihistamines block histamines, which are chemicals responsible for many allergy symptoms. Antihist...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.