Who should not take Benadryl?

Benadryl should not be taken by anyone with a known allergy to any ingredient in the product.  Benadryl may not be appropriate for everyone due to the potential interaction with a variety of medications, side effects and risks related to other medical conditions. Benadryl may not be right for you if you have these conditions:

  • glaucoma
  • ulcers
  • gastroesophageal reflux disorder
  • diabetes
  • persistent cough or cough with mucus
  • enlarged prostate
  • asthma
  • hyperthyroid disease
  • diseases of the heart
  • hypertension
  • chronic obstructive pulmonary disease

If you are currently taking or recently stopped taking a monoamine oxidase inhibitor (MAOI), you should talk to your doctor prior to taking Benadryl. Benadryl should never be used for the purpose of sedation in children.