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What is clinically isolated syndrome (CIS)?

Children and adults with multiple sclerosis (MS) can experience a phenomenon called clinically isolated syndrome (CIS). This is an attack of neurological symptoms, which may or may not go on to become relapse-remitting MS (RRMS) or another form of MS. Doctors sometimes call CIS an "initial demyelinating event." More and more, MS treatment is being started as soon as CIS is diagnosed. Doctors believe early treatment for MS may reduce the number of attacks a person has over the course of their lifetime.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.