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How do metabolic disorders affect the body?

Metabolic disorders are often inherited, meaning they are caused by genetic problems that affect the function and production of enzymes, which are chemicals that break down food. Food has important substances like fat, proteins, and carbohydrates that are normally broken down to give the body energy. When enzymes don't work correctly, or when they're not there at all, the body can't break down those substances. This causes a buildup of certain materials and a lack of others, which can lead to major health problems, which may include seizures, poor development, mental retardation, eye problems, gastrointestinal distress, lung disease, paralysis, and death. Noninherited metabolic disorders, such as hypothyroidism and type 2 diabetes, also result in a lack of or inability to use substances properly , which can cause a variety of symptoms (fatigue, organ damage, depression). 

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.